Vitamins 201: vitamin D and your immune system

This is part 2 of a 2-part series on vitamin D and why it matters.

We’re approaching cold and flu season. We’re also living with Covid-19 for the foreseeable future. Covid-19 cases tend to spike in colder months.

Does vitamin D play a role in how often you get sick and the severity of your symptoms?

Let’s take a look at the research!

Vitamin D and immune system function

Vitamin D plays a crucial role in immune function and inflammation.

Dating back to at least 1996, peer-reviewed research has shown that calcitriol (vitamin D) plays a role in the immune system.

Wide-ranging actions of calcitriol have further been hypothesized to play a potential role in preventive or therapeutic action in

cancer

chronic conditions such as auto-immune conditions (including type 1 diabetes),

cardiovascular disease, and infections.

The ability of vitamin D to exhibit anti-inflammatory effects on cancer cells by down-regulating the pro-inflammatory pathways, may contribute to cancer inhibition.

source

Photo by @edgardo1987 on Unsplash

Vitamin D and Covid-19

Testing positive

Patients with vitamin D deficiency that was not adequately treated were 77% more likely to test positive for COVID-19 than patients who were not likely vitamin D deficient, according to the University of Chicago.

Duration of symptoms

Various studies conducted before the Covid-19 pandemic showed that patients who received vitamin D supplements had a lower risk of acute respiratory infections and a shorter duration of symptoms.

A study found a 59% increased risk of severe COVID-19 infection symptoms among persons with low levels of vitamin D

source

Hospitalization

As of 2023, research across multiple studies shows “a definitive association between the protective role of vitamin D and ICU hospitalization.”

A study found a 45% increase in COVID-19 infection and a 95% increase in resulting hospitalizations.

source, source

Vitamin D supplements

Is there an upper limit to vitamin D supplementation?

Yes!

There is such thing as too much vitamin D via supplementation. An excess of vitamin D can become harmful to other processes in the body. This isn’t true of getting vitamin D from sunlight; the body won’t overdo it.

As always, talk to your doctor about what you’re taking.

Another reason to eat mushrooms. Mushrooms are the only plant food with D. They contain vitamin D2, with lesser amounts of vitamins D3 and D4.

My experience

Most of us dislike being sick. I’ll do as much as I can to prevent it.

I haven’t gotten Covid. I live in New York City. I take a the subway. I’m on airplanes. I got the first two vaccines. I haven’t had any booster shots. It’s a personal decision. If it’s not broken, don’t fix it may be the best way to describe how I think about this for myself.

I’m focused on caring for my immune system so I don’t have to spend time worrying about Covid.

New York, New York

My goal is to share the research, and my personal experience, so we can live healthier, longer; avoiding the chronic illnesses that science shows are preventable.

Were you aware of the relationship between vitamin D, your immune system, and Covid-19 outcomes? Let me know!

Cover photo by @niaid on Unsplash


Thanks for reading!

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Breast cancer: risks and prevention

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Vitamins 201: should you supplement vitamin D?